季德胜蛇药片联合刺血拔罐法治疗毒虫咬伤疗效观察

Observation on therapeutic effect of Jidesheng Antivenom Tablets combined with bloodletting cupping therapy in treating venomous insect bites

关键词: 刺血拔罐法  季德胜蛇药片  蛇咬伤  毒虫咬伤  疗效

Keywords: bloodletting cupping therapy  Jidesheng Antivenom Tablets  snake bite  venomous insect bite  curative effect

摘 要: 选取 2023 年 6 月—2024 年 12 月南京市中西医结合医院收治的 90 例毒虫咬伤患者作为研究对象,随机数字表法分为对照组和联合组,各 45 例。对照组采用常规+刺血拔罐法治疗,联合组在对照组治疗基础上加用季德胜蛇药片,均治疗 3 d。比较两组患者临床疗效、症状消失时间、治疗前后炎性因子水平、不良反应发生率。结果显示,联合组治疗总有效率 97.78%, 明显高于对照组(84.44%)(P<0.05)。治疗后联合组皮肤痒麻、灼痛、水肿、肢体麻木症候评分均低于对照组,疼痛、肿胀消退时间均短于对照组(P<0.001)。联合组白细胞介素-6、C-反应蛋白、肿瘤坏死因子-α 水平低于对照组(P<0.001)。 两组不良反应发生率差异无统计学意义(4.44% vs.6.67%)。联合组治疗蛇咬伤总有效率 100%,毒虫咬伤总有效率 95.83%。提示刺血拔罐法联合季德胜蛇药片治疗毒虫咬伤疗效显著,可有效缓解患者症状,值得推广应用。

Abstract: A total of 90 patients with venomous insect bites admitted to Nanjing Integrated Traditional Chinese and Western Medicine Hospital from June 2023 to December 2024 were selected as the research subjects, they were randomly divided into the control group and the combined group by the random number table method, with 45 cases in each group. The control group was treated with routine and bloodletting cupping therapy, and the combined group were treated with Jidesheng Antivenom Tablets on the basis of the treatment in the control group. Both groups were treated for 3 days. The clinical efficacy, symptom disappearance time, levels of inflammatory factors before and after treatment, and incidence of adverse drug reactions were compared between the two groups. The results showed that the total effective rate of the combined group was 97.78%, which was significantly higher than that of the control group (84.44%)(P<0.05). After treatment, the symptom scores of skin itching, burning pain, edema and limb numbness in the combined group were lower than those in the control group, and the subsidence time of pain and swelling in the combined group was shorter than that in the control group (P<0.001). The levels of interleukin-6, C-reactive protein and tumor necrosis factor-α in the combined group were lower than those in the control group (P<0.001). There was no significant difference in the incidence of adverse reactions between the two groups (4.44% vs. 6.67%). The total effective rate of the combined group in treating snake bites was 100%, and the total effective rate of venomous insect bites was 95.83%. It is suggested that bloodletting cupping therapy combined with Jidesheng Antivenom Tablets is effective in the treatment of promotion insect bites, which can effectively relieve the symptoms of patients and is worthy of promotion and application.